© 2024 Kansas City Public Radio
NPR in Kansas City
Play Live Radio
Next Up:
0:00 0:00
Available On Air Stations

Social Media, Math And The Mystery Of A Mumps Outbreak

In August 2016, an outbreak of mumps began in Arkansas. Since then, there have been nearly 3,000 cases of the disease across 33 counties in the state.

As a public health practitioner, I wondered: Why did this outbreak take off?

My team at HealthMap, a computational epidemiology lab based out of Boston Children's Hospital, began by rounding up as much data as we could.

We quickly discovered that the Arkansas Department of Health was releasing semi-regular PDF reports on the outbreak. The reports broke down cases by county, age and school district (many of the people who have contracted mumps in the Arkansas outbreak are children). But there were no historical archives that could give us a sense of how the outbreak had grown over time.

So we turned to a tool called the , which collects social media reports and news about public health issues around the world and turns them into usable epidemiological data. (For example, this blog previously reported on how we used our surveillance system to collect Google search and participatory public health data to track and predict flu outbreaks.)

From the HealthMap data about the mumps outbreak, we were able to estimate the total number of cases that had occurred since August 2016.

At that point, we had all the information we needed to tackle a more difficult question: What could the data tell us about vaccination in communities affected by the outbreak?

Before we get to our answer to that question, let's talk about mumps.

Mumps, like measles and rubella, is extremely contagious. Because of this, the measles-mumps-rubella, or MMR, vaccine is given in two doses. Even with both doses, the vaccine is imperfect. One out of every 10 individuals who receives it remains susceptible to the mumps virus. In the event of a mumps outbreak, some people who get sick will be people who were vaccinated; how many depends on what percentage of the people in the affected community are vaccinated.

For a disease as contagious as mumps, a two-dose community-level vaccination rate as high as 96 percent may be necessary to prevent active transmission of the virus, maintaining so-called herd immunity. When the vaccination rate drops, herd immunity breaks down and outbreaks can take off.

The Arkansas Department of Health doesn't generally report high-resolution vaccination statistics to the public. But it has been collecting self-reported data on vaccination from individuals who were diagnosed with mumps during this particular outbreak. In the department's latest report, an average of about 70 percent of people who got mumps said they had received both doses of the mumps vaccine.

However, studies have shown that self-reported vaccination rates are typically 1.5 to 2 times greater than actual vaccination rates. This means that the true two-dose vaccination rate among mumps cases in Arkansas was probably closer to 35 percent to 46 percent.

But what about vaccination rates in the larger communities that these cases came from?

After pairing our surveillance data with mathematical modeling methods, we estimated that the average two-dose vaccination rate in communities affected by the outbreak was likely no higher than 89 percent and may have been as low as 70 percent, well below that ideal rate of 96 percent.

Our complete methodology can be found in a study published Wednesday in The Lancet Infectious Diseases.

As vaccine hesitancy gains ground in the United States, we place ourselves at risk for vaccine-preventable diseases like measles, mumps and rubella. While these childhood illnesses aren't fatal to most people, those who are most susceptible to serious adverse effects, such as children under the age of 1 and cancer patients, are often those who can't be vaccinated.

And this is why herd immunity is so important. When we vaccinate, we protect not only ourselves but the most vulnerable members of our communities, too.

Update On March 31

After our study and this blog post were originally published, Dr. Dirk Haselow, the state epidemiologist and outbreak response medical director for the Arkansas Department of Health, contacted Shots to say that all vaccination rates among children in the ongoing mumps outbreak have been validated via immunization registry. However, validation of vaccination rates among adults above the age of 20 has been tricky.

"Up until 2013, our immunization registry was not allowed to retain adult immunizations," said Haselow. Because of this legislative issue, the Arkansas Department of Health has been collecting self-reported vaccination rates among adults in this age group.

As I explain, the mumps vaccine isn't 100 percent effective. Because of this, some individuals remain vulnerable to the mumps virus despite receiving the vaccine. That said, Haselow emphasized the safety and utility of the mumps vaccine. Though the vaccine isn't perfect, it seems to prevent severe symptoms among the unlucky few who are vaccinated but still get sick. Furthermore, the majority of individuals who receive both doses of the vaccine are successfully protected by it.

Because of this, the Arkansas Department of Health recommends that both children and adults check with their health care providers to ensure that they are sufficiently vaccinated against mumps.

Maimuna Majumder is an engineering systems Ph.D. candidate at the Massachusetts Institute of Technology and a computational epidemiology research fellow at HealthMap. Find her on Twitter @maiamajumder.

Copyright 2020 NPR. To see more, visit https://www.npr.org.

Corrected: March 21, 2017 at 11:00 PM CDT
Clarification: This story was updated on March 31 to include information provided by Dr. Dirk Haselow, the state epidemiologist and outbreak response medical director for the Arkansas Department of Health, about the collection of immunization data in the state. Previously posted on March 22: A previous version of this story incorrectly said the report in The Lancet Infectious Diseases was published Thursday. It was published Wednesday.
Maimuna Majumder
KCUR serves the Kansas City region with breaking news and award-winning podcasts.
Your donation helps keep nonprofit journalism free and available for everyone.