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Steve Inskeep talks with Boston Globe columnist Juliette Kayyem about city officials' decision to lock down Boston on Friday as law enforcement searched for a suspect in the Boston Marathon bombing. Kayyem is a former top homeland security official.

Defense attorney Judy Clarke routinely faces an enraged public, top-notch prosecutors and difficult, often disturbed clients. Now, she is soon to face those things again with another high-profile client, alleged Boston Marathon bomber Dzhokhar Tsarnaev.

Secretary of State John Kerry sets off for what he calls "a long overdue" trip to Russia on Monday, and Syria is likely to top the agenda. But U.S.-Russian relations are frosty these days. The U.S. is imposing targeted sanctions on Russian human rights violators, while Moscow is preventing American families from adopting Russian children.

Seft Hunter became chief operating officer last year of Communities Creating Opportunity, a faith-based organization that addresses poverty-related…

There is a lot of money to be made in bringing underage kids to the U.S. and trying to make them the next Kobe. But what happens to the rest of them?

For the first time, scientists have estimated the amount of antibiotics pigs, chickens and cows consume globally — and how fast consumption is growing. Which country uses the most drugs on farms?

After the conservative magazine declared that it is "Against Trump," it was barred from a Feb. 25 presidential debate. The move shows how delicately the Republican Party is handling Donald Trump.

NPR's Tom Goldman joins host Linda Wertheimer to talk about the NBA playoffs — is a Cleveland championship in the offing? — and Kris Bryant's debut on the diamond with the Chicago Cubs.

Big changes in 2011 — from the Arab Spring to the death of North Korea's dictator — create opportunities for 2012. But change can be scary, even when the regimes to be replaced are unpopular or repressive, because there's never a guarantee the new regime will be better.

The killing of an Iranian nuclear scientist this week marked the fifth time in two years that assassins have targeted scientists in Tehran. Weekends on All Things Considered takes a look at what this new level of diplomatic strain means for the Middle East and the U.S. economy.